Hells yes! Granted I don't like how they portrayed April O'Neil in the IDW TMNT comics but I love what they did with the Cityfall story arc and how they brought Bebop and Rocksteady back as chainsaw and sledgehammer wielding badasses!
I also like what they did with the comic book continuation for the storyline of the video games Transformers: War of Cybertron / Transformers: Fall of Cybertron.
As for their Ghostbusters comic line, well, lemme just sum it up, "WHO YA GONNA CALL"?
They had a great Star Trek/Planet of the Apes five issue series. It was the original Star Trek characters. They also has a Star Trek/Green Lantern crossover.
I read some of the Star Trek: Year Four books. Very good writing and artwork. Though I'm currently on a comic collecting hiatus, I'm impressed with the imaginative variety of titles they publish.
Their Transformers line isn't too shabby either (I mean, the ones that follow "War for Cybertron" and "Fall of Cybertron" and not the Bayverse version).