In my experience, yes. I've seen girls and women who claim they hate the be tickled, being tickled, and they laugh hysterically, and it looks genuine.
The reason, I think, is because for many people, reactions to tickling is a reflex reaction. While some people claim they can control their ticklish reactions, my experience as a very ticklish person has been that when someone starts tickling you, no matter who it is, the sensation is so intense, it causes you to laugh involuntarially.
Even though I'm a switch when it comes to tickling, I hate to be tickled by guys. Yet, when I was tickled by my male roommate in college, and guys in summer camp, I still laughed incredibly hard, even though I hated to be tickled by a guy. One male bunkmate I had used to tickle my feet all the time, and made me furious, but yet I still laughed hysterically. I could not control the laughter, even though I hated that a guy was tickling me.
Maybe this isnt true for everyone, but what I described has always been my experience.
Mitch