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Depends on the context really. My time commissioning tickling requests on sites like OF, a lot of women who say they hate being tickled come out enjoying it with a few even saying they will make it a thing. As long as it's in playful or flirty context between two consenting adults then it's all good.
I always think of Anna Kendrick as being an example of that - she describes how she broke up with a guy who wouldn't stop tickling her, but even when she talks about that it's specifically about the fact that he wouldn't listen when she kept telling him she couldn't breathe while he was doing it. A different guy who approached it a different way, respecting her limits, would probably have gotten a very different reaction from her.
I am positive this is not real. From looking at this guy's content, he seems to be doing parodies of these kinds of "social experiment" videos that they do on channels like Buzzfeed or Cut or Jubilee. I think this video is not meant to be taken seriously at all.