Sure. Lots of times. To me that is the true nature of gargalesis is the tickling of muscle tissue. Sure it may include tickling the skin on a deeper level but, muscles can be highly sensitive to tickling if someone gets you just right like when you're in a sitting position and someone squeezes your knee muscles, right behind the kneecap, sending that little thrill chill up your thigh and making you gush laughter. The same can be said for digging in to the abs or sides just right. My lower belly is nearly the worst for me but, if I clench my teeth and concentrate I can sometimes endure it to a point. On the other hand, knismesis is something else entirely and it's absolute murder for me.